Quantitative Modeling & Simulation Case Studies
PopPK Modeling for Optimized Dosing Regimen Design
For modified-release pharmaceutical formulations, PK datasets from multiple dosage variants are integrated and systematically curated to construct a robust PopPK model. Critical covariates that influence systemic pharmacokinetics (body weight, gender, age, etc.) are identified and quantified to refine safe and effective dosing regimens, supplying core modeling data for marketing authorization submissions (NDA/ANDA).
